Improving prediction of ischemic cardiovascular disease in the general population using apolipoprotein B: the Copenhagen City Heart Study.

The prediction model for cardiovascular disease using Yazd's health study data (YaHS)ta (YaHS)

Introdution: Ischemic heart disease is one of the most common diseases, which has led to high mortality rates all over the world. This disease is caused by narrowing or blockage of coronary arteries, which are the provider of blood to the heart. Identifying the people susceptible to this disease and bringing changes in their lifestyles has been said to reduce the related mortality rates and inc...

Context-dependent associations between variation in risk of ischemic heart disease and variation in the 5' promoter region of the apolipoprotein E gene in Danish women.

OBJECTIVE Variations in the noncoding single-nucleotide polymorphisms (SNPs) at positions 560 and 832 in the 5' promoter region of the apolipoprotein E gene define genotypes that distinguish between high and low concentrations of plasma total and high-density lipoprotein cholesterol and triglycerides. We addressed whether these genotypes improve the prediction of ischemic heart disease (IHD) in...

Improving Prediction of Ischemic Cardiovascular Disease in the General Population Using Apolipoprotein B

Comparison of Vitamin D Serum Level in Patients with Cardiac Ischemic and Control Group at the Heart Hospital of Hamadan City

Introduction: During the recent years, vitamin D deficiency was determined as a risk factor for cardiovascular diseases. The purpose of this study was to evaluate the association of vitamin D with ischemic heart disease in the city of Hamadan. Methods: A case control-study was performed with 72 patients with ischemic heart disease, which had been confirmed by angiography in the case group. V...

Genetically reduced soluble epoxide hydrolase activity and risk of stroke and other cardiovascular disease.

BACKGROUND AND PURPOSE The development of stroke has been linked to lowered levels of epoxyeicosatrienoic acids in the cerebral microvasculature. These substances are metabolized by the enzyme-soluble epoxide hydrolase encoded by the EPHX2 gene. We tested whether genetically reduced soluble epoxide hydrolase activity is associated with risk of ischemic stroke, myocardial infarction, and ischemi...